X-Linked Ectodermal Dysplasia (XHED) – Shepherd Type
Kodas: H385
Short description
X-Linked Ectodermal Dysplasia (XHED), also known as anhidrotic ectodermal dysplasia, is a skin and tissue disorder that results in lack of hair and underdeveloped teeth.
General information
X-Linked Ectodermal Dysplasia (XHED), also known as anhidrotic ectodermal dysplasia, is a skin and tissue disorder that results in lack of hair and underdeveloped teeth. The disorder can can leave affected dogs vulnerable to parasites and infections. It is caused by an X-linked recessive mutation to the gene EDA.
The variant of the disease analysed in this test is found in the German Shepherd. Other variants have been observed in the Dachshund and certain mixed breeds.
Specifications
| Breeds | |
|---|---|
| Gene | EDA |
| Chromosome | X |
| Mutation | c.910-1G>A |
| Organ | Digestive System |
| Specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | X-Linked Recessive |
| Also known as | XHED |
Clinical features
Affected dogs have no sweat glands or secondary hairs, and lack hair on the forehead and on the lower back. They also lack many teeth, with remaining teeth being unusually cone-shaped. Other complications from the condition can include chronic discharge from the eyes and nose, as well as susceptibility to airway infections and skin parasites.
References
Pubmed ID: 16151697
Year published: 2005
Omia ID: 543
Omia variant ID:
Turnaround information
- 10 working days