Renal Cystadenocarcinoma and Nodular Dermatofibrosis (RCND)
Kodas: H489
Short description
Renal cystadenocarcinoma and nodular dermatofibrosis (RCND) is a naturally occurring kidney cancer.
General information
Renal cystadenocarcinoma and nodular dermatofibrosis (RCND) is a naturally occurring kidney cancer. The disease is characterised by bilateral, multifocal tumors in the kidneys, uterine leiomyomas and nodules in the skin consisting of dense collagen fibers. The disease has late onset and is progressive.
Specifications
| Breeds | |
|---|---|
| Gene | FLCN |
| Chromosome | 5 |
| Mutation | c.764A>G |
| Organ | Urinary system |
| Specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | Autosomal Dominant |
| Also known as | RCND |
Clinical features
Affected dogs develop multiple firm nodules (dermatofibrosis) in the skin usually by 6 years of age. They also develop bilateral, multifocal tumors (cystadenocarcinoma) in the kidney, although the age of onset and growth rate vary.
References
Pubmed ID: 14532326
Year published: 2003
Omia ID: 1335
Omia variant ID:
Turnaround information
- 10 working days