Haemophilia B – Cairn Terrier
Kodas: H986
Short description
Haemophilia B, also called Factor IX Deficiency or Christmas Disease, is a blood disorder that impairs clotting, which can lead to uncontrolled bleeding.
General information
Haemophilia B, also called Factor IX Deficiency or Christmas Disease, is a blood disorder that impairs clotting, which can lead to uncontrolled bleeding. Haemophilia B is caused by an X-linked recessive mutation to the gene F9. There are many known variants of Haemophilia B, each specific to a particular dog breed. This variant occurs in the Cairn Terrier.
Specifications
| Breeds | |
|---|---|
| Gene | F9 |
| Chromosome | X |
| Mutation | c.1253G>A |
| Organ | Cardiovascular System |
| Specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | X-Linked Recessive |
| Also known as | Factor IX |
Clinical features
Affected dogs are prone to uncontrolled bleeding after injury or surgery, and may develop spontaneous bleeding. Blood analysis will confirm a lack of Factor IX activity and prolonged clotting times.
References
Pubmed ID: 2481310
Year published: 2021
Omia ID: 438
Omia variant ID:
Turnaround information
- 10 working days