Myeloperoxidase Deficiency
Kodas: H970
Short description
Myeloperoxidase Deficiency (MPOD) is a disorder affecting white blood cells, observed in the Italian Hound (e.
General information
Myeloperoxidase Deficiency (MPOD) is a disorder affecting white blood cells, observed in the Italian Hound (e.g. Italian Greyhound, Segugio Italiano). It is caused by a recessive mutation to the gene MPO.
Specifications
| Breeds | |
|---|---|
| Gene | MPO |
| Chromosome | 9 |
| Mutation | c.1936C>T |
| Organ | Cardiovascular System |
| Specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | Autosomal Recessive |
| Also known as | MPOD |
Clinical features
Myeloperoxidase Deficiency is primarily evident in blood analysis such as complete blood count perox. Affected white blood cells, normally stained as MPO-positive, will not be stained and cluster align in the unstained cell area.
The disorder itself is believed to lead to lead to an increased vulnerability to infections.
References
Pubmed ID: 27296514
Year published: 2016
Omia ID: 2028
Omia variant ID:
Turnaround information
- 10 working days